MRC Epidemiology Unit

The association between plasma zinc concentrations and markers of glucose metabolism in adults in Cameroon.

Mba CM, Jones KS, Forouhi NG, Imamura F, Assah F, Mbanya JC, and Wareham NJ

The British journal of nutrition. Jan 2023

Association between circulating 25-hydroxyvitamin D and cardiometabolic risk factors in adults in rural and urban settings.

Mba CM, Koulman A, Forouhi NG, Sharp SJ, Imamura F, Jones K, Meadows SR, Assah F, Mbanya JC, and Wareham NJ

Nutrition & diabetes. Jul 2022

(DOI : 10.1038/s41387-022-00215-1)

Using genetic variation to disentangle the complex relationship between food intake and health outcomes.

Pirastu N, McDonnell C, Grzeszkowiak EJ, Mounier N, Imamura F, Merino J, Day FR, Zheng J, Taba N, Concas MP, Repetto L, Kentistou KA, Robino A, Esko T, Joshi PK, Fischer K, Ong KK, Gaunt TR, Kutalik Z, Perry JRB, and Wilson JF

PLoS genetics. Jun 2022

(DOI : 10.1371/journal.pgen.1010162)

Development and validation of a metabolite score for red meat intake: an observational cohort study and randomized controlled dietary intervention.

Li C, Imamura F, Wedekind R, Stewart ID, Pietzner M, Wheeler E, Forouhi NG, Langenberg C, Scalbert A, and Wareham NJ

The American Journal of Clinical Nutrition. Dec 2021

(DOI : 10.1093/ajcn/nqac094)

Dietary Fatty Acids, Macronutrient Substitutions, Food Sources and Incidence of Coronary Heart Disease: Findings From the EPIC-CVD Case-Cohort Study Across Nine European Countries.

Steur M, Johnson L, Sharp SJ, Imamura F, Sluijs I, Key TJ, Wood A, Chowdhury R, Guevara M, Jakobsen MU, Johansson I, Koulman A, Overvad K, Sánchez MJ, van der Schouw YT, Trichopoulou A, Weiderpass E, Wennberg M, Zheng JS, Boeing H, Boer JMA, Boutron-Ruault MC, Ericson U, Heath AK, Huybrechts I, Imaz L, Kaaks R, Krogh V, Kühn T, Kyrø C, Masala G, Melander O, Moreno-Iribas C, Panico S, Quirós JR, Rodriguez-Barranco M, Sacerdote C, Santiuste C, Skeie G, Tjønneland A, Tumino R, Verschuren WMM, Zamora-Ros R, Dahm CC, Perez-Cornago A, Schulze MB, Tong TYN, Riboli E, Wareham NJ, Danesh J, Butterworth AS, and Forouhi NG

Journal of the American Heart Association. Nov 2021

(DOI : 10.1161/JAHA.120.019814)

Associations of Serum Folate and Holotranscobalamin with Cardiometabolic Risk Factors in Rural and Urban Cameroon.

Mba CM, Koulman A, Forouhi NG, Imamura F, Assah F, Mbanya JC, and Wareham NJ

Nutrients. Nov 2021

(DOI : 10.3390/nu14010178)

Milk intake and incident stroke and coronary heart disease in populations of European descent: A Mendelian Randomization study.

Vissers LET, Sluijs I, Burgess S, Forouhi NG, Freisling H, Imamura F, Nilsson TK, Renstrom F, Weiderpass E, Aleksandrova K, Dahm CC, Perez-Cornago A, Schulze MB, Tong TYN, Aune D, Bonet C, Boer JMA, Boeing H, Chirlaque MD, Conchi MI, Imaz L, Jäger S, Krogh V, Kyrø C, Masala G, Melander O, Overvad K, Panico S, Sánches MJ, Sonestedt E, Tjønneland A, Tzoulaki I, Verschuren WMM, Riboli E, Wareham NJ, Danesh J, Butterworth AS, and van der Schouw YT

The British journal of nutrition. Oct 2021

(DOI : 10.1017/S0007114521004244)

Trans Fatty Acid Biomarkers and Incident Type 2 Diabetes: Pooled Analysis of 12 Prospective Cohort Studies in the Fatty Acids and Outcomes Research Consortium (FORCE).

Lai HTM, Imamura F, Korat AVA, Murphy RA, Tintle N, Bassett JK, Chen J, Kröger J, Chien KL, Senn M, Wood AC, Forouhi NG, Schulze MB, Harris WS, Vasan RS, Hu F, Giles GG, Hodge A, Djoussé L, Brouwer IA, Qian F, Sun Q, Wu JHY, Marklund M, Lemaitre RN, Siscovick DS, Fretts AM, Shadyab AH, Manson JE, Howard BV, Robinson JG, Wallace RB, Wareham NJ, Chen YI, Rotter JI, Tsai MY, Micha R, Mozaffarian D, and Fatty Acids and Outcomes Research Consortium (FORCE)

Diabetes care. Aug 2021

(DOI : 10.2337/dc21-1756)

Sugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density Lipoprotein Cholesterol) and Triglyceride Concentrations.

Haslam DE, Peloso GM, Guirette M, Imamura F, Bartz TM, Pitsillides AN, Wang CA, Li-Gao R, Westra JM, Pitkänen N, Young KL, Graff M, Wood AC, Braun KVE, Luan J, Kähönen M, Kiefte-de Jong JC, Ghanbari M, Tintle N, Lemaitre RN, Mook-Kanamori DO, North K, Helminen M, Mossavar-Rahmani Y, Snetselaar L, Martin LW, Viikari JS, Oddy WH, Pennell CE, Rosendall FR, Ikram MA, Uitterlinden AG, Psaty BM, Mozaffarian D, Rotter JI, Taylor KD, Lehtimäki T, Raitakari OT, Livingston KA, Voortman T, Forouhi NG, Wareham NJ, de Mutsert R, Rich SS, Manson JE, Mora S, Ridker PM, Merino J, Meigs JB, Dashti HS, Chasman DI, Lichtenstein AH, Smith CE, Dupuis J, Herman MA, and McKeown NM

Circulation. Genomic and precision medicine. Jul 2021

(DOI : 10.1161/CIRCGEN.120.003288)

Prospective association between adherence to the Mediterranean diet and hepatic steatosis: the Swiss CoLaus cohort study.

Khalatbari-Soltani S, Marques-Vidal P, Imamura F, and Forouhi NG

BMJ Open. Dec 2020

(DOI : 10.1136/bmjopen-2020-040959)

Plasma Sulfur Amino Acids and Risk of Cerebrovascular Diseases: A Nested Case-Control Study in the EPIC-Norfolk Cohort.

Vinknes KJ, Refsum H, Turner C, Khaw KT, Wareham NJ, Forouhi NG, and Imamura F

Stroke. Dec 2020

(DOI : 10.1161/STROKEAHA.120.029177)

n-3 Fatty Acid Biomarkers and Incident Type 2 Diabetes: An Individual Participant-Level Pooling Project of 20 Prospective Cohort Studies.

Qian F, Ardisson Korat AV, Imamura F, Marklund M, Tintle N, Virtanen JK, Zhou X, Bassett JK, Lai H, Hirakawa Y, Chien KL, Wood AC, Lankinen M, Murphy RA, Samieri C, Pertiwi K, de Mello VD, Guan W, Forouhi NG, Wareham N, Hu ICFB, Riserus U, Lind L, Harris WS, Shadyab AH, Robinson JG, Steffen LM, Hodge A, Giles GG, Ninomiya T, Uusitupa M, Tuomilehto J, Lindström J, Laakso M, Siscovick DS, Helmer C, Geleijnse JM, Wu JHY, Fretts A, Lemaitre RN, Micha R, Mozaffarian D, Sun Q, and Fatty Acids and Outcomes Research Consortium (FORCE)

Diabetes care. Sep 2020

(DOI : 10.2337/dc20-2426)

Using nutritional survey data to inform the design of sugar-sweetened beverage taxes in low-resource contexts: a cross-sectional analysis based on data from an adult Caribbean population.

Alvarado M, Harris R, Rose A, Unwin N, Hambleton I, Imamura F, and Adams J

BMJ Open. Sep 2020

(DOI : 10.1136/bmjopen-2019-035981)

Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies.

Harris WS, Tintle NL, Imamura F, Qian F, Korat AVA, Marklund M, Djoussé L, Bassett JK, Carmichael PH, Chen YY, Hirakawa Y, Küpers LK, Laguzzi F, Lankinen M, Murphy RA, Samieri C, Senn MK, Shi P, Virtanen JK, Brouwer IA, Chien KL, Eiriksdottir G, Forouhi NG, Geleijnse JM, Giles GG, Gudnason V, Helmer C, Hodge A, Jackson R, Khaw KT, Laakso M, Lai H, Laurin D, Leander K, Lindsay J, Micha R, Mursu J, Ninomiya T, Post W, Psaty BM, Riserus U, Robinson JG, Shadyab AH, Snetselaar L, Sala-Vila A, Sun Y, Steffen LM, Tsai MY, Wareham NJ, Wood AC, Wu JHY, Hu F, Sun Q, Siscovick DS, Lemaitre RN, Mozaffarian D, and Fatty Acids and Outcomes Research Consortium (FORCE)

Nature communications. Aug 2020

(DOI : 10.1038/s41467-021-22370-2)

Associations of Total Legume, Pulse, and Soy Consumption with Incident Type 2 Diabetes: Federated Meta-Analysis of 27 Studies from Diverse World Regions.

Pearce M, Fanidi A, Bishop TRP, Sharp SJ, Imamura F, Dietrich S, Akbaraly T, Bes-Rastrollo M, Beulens JWJ, Byberg L, Canhada S, Molina MDCB, Chen Z, Cortes-Valencia A, Du H, Duncan BB, Härkänen T, Hashemian M, Kim J, Kim MK, Kim Y, Knekt P, Kromhout D, Lassale C, Ridaura RL, Magliano DJ, Malekzadeh R, Marques-Vidal P, Martínez-González MÁ, O'Donoghue G, O'Gorman D, Shaw JE, Soedamah-Muthu SS, Stern D, Wolk A, Woo HW, EPIC-InterAct Consortium, Wareham NJ, and Forouhi NG

The Journal of nutrition. Aug 2020

(DOI : 10.1093/jn/nxaa447)

Association of plasma biomarkers of fruit and vegetable intake with incident type 2 diabetes: EPIC-InterAct case-cohort study in eight European countries.

Zheng JS, Sharp SJ, Imamura F, Chowdhury R, Gundersen TE, Steur M, Sluijs I, van der Schouw YT, Agudo A, Aune D, Barricarte A, Boeing H, Chirlaque MD, Dorronsoro M, Freisling H, El-Fatouhi D, Franks PW, Fagherazzi G, Grioni S, Gunter MJ, Kyrø C, Katzke V, Kühn T, Khaw KT, Laouali N, Masala G, Nilsson PM, Overvad K, Panico S, Papier K, Quirós JR, Rolandsson O, Redondo-Sánchez D, Ricceri F, Schulze MB, Spijkerman AMW, Tjønneland A, Tong TYN, Tumino R, Weiderpass E, Danesh J, Butterworth AS, Riboli E, Forouhi NG, and Wareham NJ

BMJ (Clinical research ed.). Jul 2020

(DOI : 10.1136/bmj.m2194)

Plasma Vitamin C and Type 2 Diabetes: Genome-Wide Association Study and Mendelian Randomization Analysis in European Populations.

Zheng JS, Luan J, Sofianopoulou E, Imamura F, Stewart ID, Day FR, Pietzner M, Wheeler E, Lotta LA, Gundersen TE, Amiano P, Ardanaz E, Chirlaque MD, Fagherazzi G, Franks PW, Kaaks R, Laouali N, Mancini FR, Nilsson PM, Onland-Moret NC, Olsen A, Overvad K, Panico S, Palli D, Ricceri F, Rolandsson O, Spijkerman AMW, Sánchez MJ, Schulze MB, Sala N, Sieri S, Tjønneland A, Tumino R, van der Schouw YT, Weiderpass E, Riboli E, Danesh J, Butterworth AS, Sharp SJ, Langenberg C, Forouhi NG, and Wareham NJ

Diabetes care. Jun 2020

(DOI : 10.2337/dc20-1328)

Mediterranean diet and risk of Sjögren's syndrome.

Machowicz A, Hall I, de Pablo P, Rauz S, Richards A, Higham J, Poveda-Gallego A, Imamura F, Bowman SJ, Barone F, and Fisher BA

Clinical and experimental rheumatology. May 2020

(DOI : 15905)

Replacement of Red and Processed Meat With Other Food Sources of Protein and the Risk of Type 2 Diabetes in European Populations: The EPIC-InterAct Study.

Ibsen DB, Steur M, Imamura F, Overvad K, Schulze MB, Bendinelli B, Guevara M, Agudo A, Amiano P, Aune D, Barricarte A, Ericson U, Fagherazzi G, Franks PW, Freisling H, Quirós JR, Grioni S, Heath AK, Huybrechts I, Katze V, Laouali N, Mancini F, Masala G, Olsen A, Papier K, Ramne S, Rolandsson O, Sacerdote C, Sánchez MJ, Santiuste C, Simeon V, Spijkerman AMW, Srour B, Tjønneland A, Tong TYN, Tumino R, van der Schouw YT, Weiderpass E, Wittenbecher C, Sharp SJ, Riboli E, Forouhi NG, and Wareham NJ

Diabetes care. May 2020

(DOI : 10.2337/dc20-1038)

Erythrocyte n-6 Polyunsaturated Fatty Acids, Gut Microbiota, and Incident Type 2 Diabetes: A Prospective Cohort Study.

Miao Z, Lin JS, Mao Y, Chen GD, Zeng FF, Dong HL, Jiang Z, Wang J, Xiao C, Shuai M, Gou W, Fu Y, Imamura F, Chen YM, and Zheng JS

Diabetes care. Mar 2020

(DOI : 10.2337/dc20-0631)

Insights into genetic variants associated with NASH-fibrosis from metabolite profiling.

Mann JP, Pietzner M, Wittemans LB, Rolfe EL, Kerrison ND, Imamura F, Forouhi NG, Fauman E, Allison ME, Griffin JL, Koulman A, Wareham NJ, and Langenberg C

Human Molecular Genetics. Mar 2020

(DOI : 10.1093/hmg/ddaa162)

A cross-platform approach identifies genetic regulators of human metabolism and health.

Lotta LA, Pietzner M, Stewart ID, Wittemans LBL, Li C, Bonelli R, Raffler J, Biggs EK, Oliver-Williams C, Auyeung VPW, Luan J, Wheeler E, Paige E, Surendran P, Michelotti GA, Scott RA, Burgess S, Zuber V, Sanderson E, Koulman A, Imamura F, Forouhi NG, Khaw KT, MacTel Consortium, Griffin JL, Wood AM, Kastenmüller G, Danesh J, Butterworth AS, Gribble FM, Reimann F, Bahlo M, Fauman E, Wareham NJ, and Langenberg C

Nature genetics. Feb 2020

(DOI : 10.1038/s41588-020-00751-5)

Prospective association of soft drink consumption with depressive symptoms.

Kashino I, Kochi T, Imamura F, Eguchi M, Kuwahara K, Nanri A, Kurotani K, Akter S, Hu H, Miki T, Kabe I, and Mizoue T

Nutrition (Burbank, Los Angeles County, Calif.). Dec 2019

(DOI : 10.1016/j.nut.2020.110860)

Genetic study of the Arctic CPT1A variant suggests that its effect on fatty acid levels is modulated by traditional Inuit diet.

Senftleber N, Jørgensen ME, Jørsboe E, Imamura F, Forouhi NG, Larsen CL, Bjerregaard P, Hansen T, and Albrechtsen A

European journal of human genetics : EJHG. Dec 2019

(DOI : 10.1038/s41431-020-0674-0)

The associations of longitudinal changes in consumption of total and types of dairy products and markers of metabolic risk and adiposity: findings from the European Investigation into Cancer and Nutrition (EPIC)-Norfolk study, United Kingdom.

Trichia E, Luben R, Khaw KT, Wareham NJ, Imamura F, and Forouhi NG

The American Journal of Clinical Nutrition. Oct 2019

(DOI : 10.1093/ajcn/nqz335)

Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies.

Imamura F, Fretts AM, Marklund M, Ardisson Korat AV, Yang WS, Lankinen M, Qureshi W, Helmer C, Chen TA, Virtanen JK, Wong K, Bassett JK, Murphy R, Tintle N, Yu CI, Brouwer IA, Chien KL, Chen YY, Wood AC, Del Gobbo LC, Djoussé L, Geleijnse JM, Giles GG, de Goede J, Gudnason V, Harris WS, Hodge A, Hu F, InterAct Consortium, Koulman A, Laakso M, Lind L, Lin HJ, McKnight B, Rajaobelina K, Riserus U, Robinson JG, Samieri C, Senn M, Siscovick DS, Soedamah-Muthu SS, Sotoodehnia N, Sun Q, Tsai MY, Tuomainen TP, Uusitupa M, Wagenknecht LE, Wareham NJ, Wu JHY, Micha R, Lemaitre RN, Mozaffarian D, and Forouhi NG

PLoS Medicine. Oct 2019

(DOI : 10.1371/journal.pmed.1003102)

The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis.

Zheng JS, Luan J, Sofianopoulou E, Sharp SJ, Day FR, Imamura F, Gundersen TE, Lotta LA, Sluijs I, Stewart ID, Shah RL, van der Schouw YT, Wheeler E, Ardanaz E, Boeing H, Dorronsoro M, Dahm CC, Dimou N, El-Fatouhi D, Franks PW, Fagherazzi G, Grioni S, Huerta JM, Heath AK, Hansen L, Jenab M, Jakszyn P, Kaaks R, Kühn T, Khaw KT, Laouali N, Masala G, Nilsson PM, Overvad K, Olsen A, Panico S, Quirós JR, Rolandsson O, Rodriguez-Barranco M, Sacerdote C, Spijkerman AMW, Tong TYN, Tumino R, Tsilidis KK, Danesh J, Riboli E, Butterworth AS, Langenberg C, Forouhi NG, and Wareham NJ

PLoS Medicine. Sep 2019

(DOI : 10.1371/journal.pmed.1003394)

Associations of types of dairy consumption with adiposity: cross-sectional findings from over 12,000 adults in the Fenland Study, UK.

Trichia E, Imamura F, Brage S, De Lucia Rolfe E, Griffin SJ, Wareham NJ, and Forouhi NG

The British journal of nutrition. Jul 2019

(DOI : 10.1017/S0007114519001776)

A Combination of Metabolites Predicts Adherence to the Mediterranean Diet Pattern and Its Associations with Insulin Sensitivity and Lipid Homeostasis in the General Population: The Fenland Study, United Kingdom.

Tong TYN, Koulman A, Griffin JL, Wareham NJ, Forouhi NG, and Imamura F

The Journal of nutrition. Jun 2019

(DOI : 10.1093/jn/nxz263)

The associations of major foods and fibre with risks of ischaemic and haemorrhagic stroke: a prospective study of 418 329 participants in the EPIC cohort across nine European countries.

Tong TYN, Appleby PN, Key TJ, Dahm CC, Overvad K, Olsen A, Tjønneland A, Katzke V, Kühn T, Boeing H, Karakatsani A, Peppa E, Trichopoulou A, Weiderpass E, Masala G, Grioni S, Panico S, Tumino R, Boer JMA, Verschuren WMM, Quirós JR, Agudo A, Rodriguez-Barranco M, Imaz L, Chirlaque MD, Moreno-Iribas C, Engström G, Sonestedt E, Lind M, Otten J, Khaw KT, Aune D, Riboli E, Wareham NJ, Imamura F, Forouhi NG, Di Angelantonio E, Wood AM, Butterworth AS, and Perez-Cornago A

European heart journal. Jun 2019

(DOI : 10.1093/eurheartj/ehaa007)

Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality.

Marklund M, Wu JHY, Imamura F, Del Gobbo LC, Fretts A, de Goede J, Tintle N, Wennberg M, Aslibekyan S, Chen TA, de Oliveira Otto MC, Kröger J, Laguzzi F, Lankinen M, Murphy RA, Samieri C, Wood AC, Wong K, Yang WS, Zhou X, Boer JMA, Brouwer IA, Chien KL, de Faire U, Djoussé L, Eiriksdottir G, Forouhi NG, Geleijnse JM, Gigante B, Gudnason V, Harris WS, Helmer C, Hodge A, Jansson JH, Kalsbeek A, Khaw KT, Koh WP, Laakso M, Leander K, Lin HJ, Lind L, Luben R, McKnight B, Ninomiya T, Overvad K, Psaty BM, Schulze MB, Siscovick D, Smith AV, Steffen BT, Sundström J, Tsai MY, van Dam RM, Veenstra J, Wareham NJ, Woodward M, Yuan JM, Micha R, Lemaitre RN, Mozaffarian D, and Riserus U

Circulation. May 2019

(DOI : 10.1161/CIRCULATIONAHA.118.038908)

Validity and reliability of an online self-report 24-h dietary recall method (Intake24): a doubly labelled water study and repeated-measures analysis.

Foster E, Lee C, Imamura F, Hollidge SE, Westgate KL, Venables MC, Poliakov I, Rowland MK, Osadchiy T, Bradley JC, Simpson EL, Adamson AJ, Olivier P, Wareham N, Forouhi NG, and Brage S

Journal of nutritional science. Apr 2019

(DOI : 10.1017/jns.2019.20)

Driving status, travel modes and accelerometer-assessed physical activity in younger, middle-aged and older adults: a prospective study of 90 810 UK Biobank participants.

Hajna S, White T, Panter J, Brage S, Wijndaele K, Woodcock J, Ogilvie D, Imamura F, and Griffin SJ

International Journal of Epidemiology. Mar 2019

(DOI : 10.1093/ije/dyz065)

Estimated Substitution of Tea or Coffee for Sugar-Sweetened Beverages Was Associated with Lower Type 2 Diabetes Incidence in Case-Cohort Analysis across 8 European Countries in the EPIC-InterAct Study.

Imamura F, Schulze MB, Sharp SJ, Guevara M, Romaguera D, Bendinelli B, Salamanca-Fernández E, Ardanaz E, Arriola L, Aune D, Boeing H, Dow C, Fagherazzi G, Franks PW, Freisling H, Jakszyn P, Kaaks R, Khaw KT, Kühn T, Mancini FR, Masala G, Chirlaque MD, Nilsson PM, Overvad K, Pala VM, Panico S, Perez-Cornago A, Quirós JR, Ricceri F, Rodriguez-Barranco M, Rolandsson O, Sluijs I, Stepien M, Spijkerman AMW, Tjønneland A, Tong TYN, Tumino R, Vissers LET, Ward HA, Langenberg C, Riboli E, Forouhi NG, and Wareham NJ

The Journal of nutrition. Feb 2019

(DOI : 10.1093/jn/nxz156)

Association of alcohol consumption with prevalence of fatty liver after adjustment for dietary patterns: Cross-sectional analysis of Japanese middle-aged adults.

Tajima R, Imamura F, Kimura T, Kobayashi S, Masuda K, and Iida K

Clinical nutrition (Edinburgh, Scotland). Jan 2019

(DOI : 10.1016/j.clnu.2019.07.001)

Changes in plasma phospholipid fatty acid profiles over 13 years and correlates of change: European Prospective Investigation into Cancer and Nutrition-Norfolk Study.

Zheng JS, Imamura F, Sharp SJ, Koulman A, Griffin JL, Mulligan AA, Luben R, Khaw KT, Wareham NJ, and Forouhi NG

The American Journal of Clinical Nutrition. Dec 2018

(DOI : 10.1093/ajcn/nqz030)

The obesity transition: stages of the global epidemic.

Jaacks LM, Vandevijvere S, Pan A, McGowan CJ, Wallace C, Imamura F, Mozaffarian D, Swinburn B, and Ezzati M

The lancet. Diabetes & endocrinology. Dec 2018

(DOI : 10.1016/S2213-8587(19)30026-9)

Associations of circulating very-long-chain saturated fatty acids and incident type 2 diabetes: a pooled analysis of prospective cohort studies.

Fretts AM, Imamura F, Marklund M, Micha R, Wu JHY, Murphy RA, Chien KL, McKnight B, Tintle N, Forouhi NG, Qureshi WT, Virtanen JK, Wong K, Wood AC, Lankinen M, Rajaobelina K, Harris TB, Djoussé L, Harris B, Wareham NJ, Steffen LM, Laakso M, Veenstra J, Samieri C, Brouwer IA, Yu CI, Koulman A, Steffen BT, Helmer C, Sotoodehnia N, Siscovick D, Gudnason V, InterAct Consortium InterAct Consortium, Wagenknecht L, Voutilainen S, Tsai MY, Uusitupa M, Kalsbeek A, Berr C, Mozaffarian D, and Lemaitre RN

The American Journal of Clinical Nutrition. Oct 2018

(DOI : 10.1093/ajcn/nqz005)

Genomic analysis of diet composition finds novel loci and associations with health and lifestyle.

Meddens SFW, de Vlaming R, Bowers P, Burik CAP, Linnér RK, Lee C, Okbay A, Turley P, Rietveld CA, Fontana MA, Ghanbari M, Imamura F, McMahon G, van der Most PJ, Voortman T, Wade KH, Anderson EL, Braun KVE, Emmett PM, Esko T, González JR, Kiefte-de Jong JC, Langenberg C, Luan J, Muka T, Ring S, Rivadeneira F, Snieder H, van Rooij FJA, Wolffenbuttel BHR, 23andMe Research Team, EPIC- InterAct Consortium, Lifelines Cohort Study, Smith GD, Franco OH, Forouhi NG, Ikram MA, Uitterlinden AG, Van Vliet-Ostaptchouk JV, Wareham NJ, Cesarini D, Harden KP, Lee JJ, Benjamin DJ, Chow CC, and Koellinger PD

Molecular psychiatry. Oct 2018

(DOI : 10.1038/s41380-020-0697-5)

Dairy Product Intake and Risk of Type 2 Diabetes in EPIC-InterAct: A Mendelian Randomization Study.

Vissers LET, Sluijs I, van der Schouw YT, Forouhi NG, Imamura F, Burgess S, Barricarte A, Boeing H, Bonet C, Chirlaque MD, Fagherazzi G, Franks PW, Freisling H, Gunter MJ, Quirós JR, Ibsen DB, Kaaks R, Khaw KT, Kühn T, Nilsson PM, Overvad K, Pala V, Palli D, Panico S, Sacerdote C, Spijkerman AMW, Tjonneland A, Tumino R, Rodriguez-Barranco M, Rolandsson O, Riboli E, Sharp SJ, Langenberg C, and Wareham NJ

Diabetes care. Sep 2018

(DOI : 10.2337/dc18-2034)

Preventable Cancer Burden Associated With Poor Diet in the United States.

Zhang FF, Cudhea F, Shan Z, Michaud DS, Imamura F, Eom H, Ruan M, Rehm CD, Liu J, Du M, Kim D, Lizewski L, Wilde P, and Mozaffarian D

JNCI cancer spectrum. Sep 2018

(DOI : 10.1093/jncics/pkz034)

The association between adherence to the Mediterranean diet and hepatic steatosis: cross-sectional analysis of two independent studies, the UK Fenland Study and the Swiss CoLaus Study.

Imamura F, Brage S, De Lucia Rolfe E, Griffin SJ, Wareham NJ, Marques-Vidal P, and Forouhi NG

BMC medicine. Aug 2018

(DOI : 10.1186/s12916-019-1251-7)

Association of Plasma Vitamin D Metabolites With Incident Type 2 Diabetes: EPIC-InterAct Case-Cohort Study.

Zheng JS, Imamura F, Sharp SJ, van der Schouw YT, Sluijs I, Gundersen TE, Ardanaz E, Boeing H, Bonet C, Gómez JH, Dow C, Fagherazzi G, Franks PW, Jenab M, Kühn T, Kaaks R, Key TJ, Khaw KT, Lasheras C, Mokoroa O, Mancini FR, Nilsson PM, Overvad K, Panico S, Palli D, Rolandsson O, Sieri S, Salamanca-Fernández E, Sacerdote C, Spijkerman AMW, Stepien M, Tjonneland A, Tumino R, Butterworth AS, Riboli E, Danesh J, Langenberg C, Forouhi NG, and Wareham NJ

The Journal of clinical endocrinology and metabolism. Jul 2018

(DOI : 10.1210/jc.2018-01522)

Assessing the causal association of glycine with risk of cardio-metabolic diseases.

Wittemans LBL, Lotta LA, Oliver-Williams C, Stewart ID, Surendran P, Karthikeyan S, Day FR, Koulman A, Imamura F, Zeng L, Erdmann J, Schunkert H, Khaw KT, Griffin JL, Forouhi NG, Scott RA, Wood AM, Burgess S, Howson JMM, Danesh J, Wareham NJ, Butterworth AS, and Langenberg C

Nature communications. Jul 2018

(DOI : 10.1038/s41467-019-08936-1)

Circulating Phylloquinone Concentrations and Risk of Type 2 Diabetes: A Mendelian Randomization Study.

Zwakenberg SR, Remmelzwaal S, Beulens JWJ, Booth SL, Burgess S, Dashti HS, Imamura F, Feskens EJM, van der Schouw YT, and Sluijs I

Diabetes. May 2018

(DOI : 10.2337/db18-0543)

Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies.

Imamura F, Fretts A, Marklund M, Ardisson Korat AV, Yang WS, Lankinen M, Qureshi W, Helmer C, Chen TA, Wong K, Bassett JK, Murphy R, Tintle N, Yu CI, Brouwer IA, Chien KL, Frazier-Wood AC, Del Gobbo LC, Djoussé L, Geleijnse JM, Giles GG, de Goede J, Gudnason V, Harris WS, Hodge A, Hu F, InterAct Consortium, Koulman A, Laakso M, Lind L, Lin HJ, McKnight B, Rajaobelina K, Riserus U, Robinson JG, Samieri C, Siscovick DS, Soedamah-Muthu SS, Sotoodehnia N, Sun Q, Tsai MY, Uusitupa M, Wagenknecht LE, Wareham NJ, Wu JH, Micha R, Forouhi NG, Lemaitre RN, Mozaffarian D, and Fatty Acids and Outcomes Research Consortium (FORCE)

PLoS Medicine. Apr 2018

(DOI : 10.1371/journal.pmed.1002670)

Dietary cost associated with adherence to the Mediterranean diet, and its variation by socio-economic factors in the UK Fenland Study.

Tong TYN, Imamura F, Monsivais P, Brage S, Griffin SJ, Wareham NJ, and Forouhi NG

The British journal of nutrition. Mar 2018

(DOI : 10.1017/S0007114517003993)

A Meta-Analysis of Food Labeling Effects on Consumer Diet Behaviors and Industry Practices.

Shangguan S, Afshin A, Shulkin M, Ma W, Marsden D, Smith J, Saheb-Kashaf M, Shi P, Micha R, Imamura F, Mozaffarian D, and Food PRICE (Policy Review and Intervention Cost-Effectiveness) Project Food PRICE (Policy Review and Intervention Cost-Effectiveness) Project

American Journal of Preventive Medicine. Jan 2018

(DOI : 10.1016/j.amepre.2018.09.024)

Assessing dietary intakes from household budget surveys: A national analysis in Bangladesh.

Karageorgou D, Imamura F, Zhang J, Shi P, Mozaffarian D, and Micha R

PLoS ONE. Jan 2018

(DOI : 10.1371/journal.pone.0202831)

Genome-wide association study for risk taking propensity indicates shared pathways with body mass index.

Clifton EAD, Perry JRB, Imamura F, Lotta LA, Brage S, Forouhi NG, Griffin SJ, Wareham NJ, Ong KK, and Day FR

Communications biology. Oct 2017

(DOI : 10.1038/s42003-018-0042-6)

Interplay between genetic predisposition, macronutrient intake and type 2 diabetes incidence: analysis within EPIC-InterAct across eight European countries.

Li SX, Imamura F, Schulze MB, Zheng J, Ye Z, Agudo A, Ardanaz E, Aune D, Boeing H, Dorronsoro M, Dow C, Fagherazzi G, Grioni S, Gunter MJ, Huerta JM, Ibsen DB, Jakobsen MU, Kaaks R, Key TJ, Khaw KT, Kyrø C, Mancini FR, Molina-Portillo E, Murphy N, Nilsson PM, Onland-Moret NC, Palli D, Panico S, Poveda A, Quirós JR, Ricceri F, Sluijs I, Spijkerman AMW, Tjonneland A, Tumino R, Winkvist A, Langenberg C, Sharp SJ, Riboli E, Scott RA, Forouhi NG, and Wareham NJ

Diabetologia. Oct 2017

(DOI : 10.1007/s00125-018-4586-2)

Sociodemographic, lifestyle and behavioural factors associated with consumption of sweetened beverages among adults in Cambridgeshire, UK: the Fenland Study.

Barrett P, Imamura F, Brage S, Griffin SJ, Wareham NJ, and Forouhi NG

Public Health Nutrition. Aug 2017

(DOI : 10.1017/S136898001700177X)

Hepatic steatosis risk is partly driven by increased de novo lipogenesis following carbohydrate consumption.

Sanders FWB, Acharjee A, Walker C, Marney L, Roberts LD, Imamura F, Jenkins B, Case J, Ray S, Virtue S, Vidal-Puig A, Kuh D, Hardy R, Allison M, Forouhi N, Murray AJ, Wareham N, Vacca M, Koulman A, and Griffin JL

Genome biology. Jul 2017

(DOI : 10.1186/s13059-018-1439-8)

Association between plasma phospholipid saturated fatty acids and metabolic markers of lipid, hepatic, inflammation and glycaemic pathways in eight European countries: a cross-sectional analysis in the EPIC-InterAct study.

Zheng JS, Sharp SJ, Imamura F, Koulman A, Schulze MB, Ye Z, Griffin J, Guevara M, Huerta JM, Kröger J, Sluijs I, Agudo A, Barricarte A, Boeing H, Colorado-Yohar S, Dow C, Dorronsoro M, Dinesen PT, Fagherazzi G, Franks PW, Feskens EJM, Kühn T, Katzke VA, Key TJ, Khaw KT, De Magistris MS, Mancini FR, Molina-Portillo E, Nilsson PM, Olsen A, Overvad K, Palli D, Quirós JR, Rolandsson O, Ricceri F, Spijkerman AMW, Slimani N, Tagliabue G, Tjonneland A, Tumino R, van der Schouw YT, Langenberg C, Riboli E, Forouhi NG, and Wareham NJ

BMC medicine. Jun 2017

(DOI : 10.1186/s12916-017-0968-4)

A combination of plasma phospholipid fatty acids and its association with incidence of type 2 diabetes: The EPIC-InterAct case-cohort study.

Imamura F, Sharp SJ, Koulman A, Schulze MB, Kröger J, Griffin JL, Huerta JM, Guevara M, Sluijs I, Agudo A, Ardanaz E, Balkau B, Boeing H, Chajès V, Dahm CC, Fagherazzi G, Franks PW, Gavrila D, Gunter M, Kaaks R, Key TJ, Khaw KT, Kühn T, Melander O, Molina-Portillo E, Nilsson PM, Olsen A, Overvad K, Palli D, Panico S, Rolandsson O, Sieri S, Sacerdote C, Slimani N, Tjønneland A, Tumino R, van der Schouw YT, Langenberg C, Riboli E, Forouhi NG, and Wareham NJ

PLoS Medicine. Jun 2017

(DOI : 10.1371/journal.pmed.1002409)

Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39 740 adults from 20 prospective cohort studies.

Wu JHY, Marklund M, Imamura F, Tintle N, Ardisson Korat AV, de Goede J, Zhou X, Yang WS, de Oliveira Otto MC, Kröger J, Qureshi W, Virtanen JK, Bassett JK, Frazier-Wood AC, Lankinen M, Murphy RA, Rajaobelina K, Del Gobbo LC, Forouhi NG, Luben R, Khaw KT, Wareham N, Kalsbeek A, Veenstra J, Luo J, Hu FB, Lin HJ, Siscovick DS, Boeing H, Chen TA, Steffen B, Steffen LM, Hodge A, Eriksdottir G, Smith AV, Gudnason V, Harris TB, Brouwer IA, Berr C, Helmer C, Samieri C, Laakso M, Tsai MY, Giles GG, Nurmi T, Wagenknecht L, Schulze MB, Lemaitre RN, Chien KL, Soedamah-Muthu SS, Geleijnse JM, Sun Q, Harris WS, Lind L, Ärnlöv J, Riserus U, Micha R, Mozaffarian D, and Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE)

The lancet. Diabetes & endocrinology. Jun 2017

(DOI : 10.1016/S2213-8587(17)30307-8)

Association Between Dietary Factors and Mortality From Heart Disease, Stroke, and Type 2 Diabetes in the United States.

Micha R, Peñalvo JL, Cudhea F, Imamura F, Rehm CD, and Mozaffarian D

JAMA. Mar 2017

(DOI : 10.1001/jama.2017.0947)

Interaction between genes and macronutrient intake on the risk of developing type 2 diabetes: systematic review and findings from European Prospective Investigation into Cancer (EPIC)-InterAct.

Li SX, Imamura F, Ye Z, Schulze MB, Zheng J, Ardanaz E, Arriola L, Boeing H, Dow C, Fagherazzi G, Franks PW, Agudo A, Grioni S, Kaaks R, Katzke VA, Key TJ, Khaw KT, Mancini FR, Navarro C, Nilsson PM, Onland-Moret NC, Overvad K, Palli D, Panico S, Quirós JR, Rolandsson O, Sacerdote C, Sánchez MJ, Slimani N, Sluijs I, Spijkerman AM, Tjonneland A, Tumino R, Sharp SJ, Riboli E, Langenberg C, Scott RA, Forouhi NG, and Wareham NJ

The American Journal of Clinical Nutrition. Dec 2016

(DOI : 10.3945/ajcn.116.150094)

Intakes and sources of dietary sugars and their association with metabolic and inflammatory markers.

O'Connor L, Imamura F, Brage S, Griffin SJ, Wareham NJ, and Forouhi NG

Clinical nutrition (Edinburgh, Scotland). Aug 2016

(DOI : 10.1016/j.clnu.2017.05.030)

Intakes and sources of dietary sugars and their association with metabolic and inflammatory markers.

O'Connor L, Imamura F, Brage S, Griffin SJ, Wareham NJ, and Forouhi NG

Clinical nutrition (Edinburgh, Scotland). Aug 2016

(DOI : 10.1016/j.clnu.2017.05.030)

Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.

Lotta LA, Scott RA, Sharp SJ, Burgess S, Luan J, Tillin T, Schmidt AF, Imamura F, Stewart ID, Perry JR, Marney L, Koulman A, Karoly ED, Forouhi NG, Sjögren RJ, Näslund E, Zierath JR, Krook A, Savage DB, Griffin JL, Chaturvedi N, Hingorani AD, Khaw KT, Barroso I, McCarthy MI, O'Rahilly S, Wareham NJ, and Langenberg C

PLoS Medicine. Aug 2016

(DOI : 10.1371/journal.pmed.1002179)

Prospective association of the Mediterranean diet with cardiovascular disease incidence and mortality and its population impact in a non-Mediterranean population: the EPIC-Norfolk study.

Tong TY, Wareham NJ, Khaw KT, Imamura F, and Forouhi NG

BMC medicine. Jul 2016

(DOI : 10.1186/s12916-016-0677-4)

ω-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease: Pooling Project of 19 Cohort Studies.

Del Gobbo LC, Imamura F, Aslibekyan S, Marklund M, Virtanen JK, Wennberg M, Frazier-Wood AC, Fretts AM, Guallar E, Prem K, Tanaka T, Zhou X, Helmer C, Ingelsson E, Yuan JM, Campos H, Djoussé L, Giles GG, Hu FB, Jansson JH, Johansson I, Khaw KT, Koh WP, Lemaitre RN, Lind L, Luben RN, Rimm EB, Riserus U, Samieri C, Franks PW, Siscovick DS, Stampfer M, Steffen LM, Steffen BT, Tsai MY, van Dam RM, Voutilainen S, Willett WC, Woodward M, and Mozaffarian D

JAMA internal medicine. Jul 2016

(DOI : 10.1001/jamainternmed.2016.2925)

Association of Plasma Phospholipid n-3 and n-6 Polyunsaturated Fatty Acids with Type 2 Diabetes: The EPIC-InterAct Case-Cohort Study.

Forouhi NG, Imamura F, Sharp SJ, Koulman A, Schulze MB, Zheng J, Ye Z, Sluijs I, Guevara M, Huerta JM, Kröger J, Wang LY, Summerhill K, Griffin JL, Feskens EJ, Affret A, Amiano P, Boeing H, Dow C, Fagherazzi G, Franks PW, Gonzalez C, Kaaks R, Key TJ, Khaw KT, Kühn T, Mortensen LM, Nilsson PM, Overvad K, Pala V, Palli D, Panico S, Quirós JR, Rodriguez-Barranco M, Rolandsson O, Sacerdote C, Scalbert A, Slimani N, Spijkerman AM, Tjonneland A, Tormo MJ, Tumino R, van der A DL, van der Schouw YT, Langenberg C, Riboli E, and Wareham NJ

PLoS Medicine. May 2016

(DOI : 10.1371/journal.pmed.1002094)

Dose-response relationship between sports activity and musculoskeletal pain in adolescents.

Kamada M, Abe T, Kitayuguchi J, Imamura F, Lee IM, Kadowaki M, Sawada SS, Miyachi M, Matsui Y, and Uchio Y

Pain. Feb 2016

(DOI : 10.1097/j.pain.0000000000000529)

Serum metabolomics profiles in response to n-3 fatty acids in Chinese patients with type 2 diabetes: a double-blind randomised controlled trial.

Zheng JS, Lin M, Imamura F, Cai W, Wang L, Feng JP, Ruan Y, Tang J, Wang F, Yang H, and Li D

Scientific reports. Feb 2016

(DOI : 10.1038/srep29522)

Effects of Saturated Fat, Polyunsaturated Fat, Monounsaturated Fat, and Carbohydrate on Glucose-Insulin Homeostasis: A Systematic Review and Meta-analysis of Randomised Controlled Feeding Trials.

Imamura F, Micha R, Wu JH, de Oliveira Otto MC, Otite FO, Abioye AI, and Mozaffarian D

PLoS Medicine. Aug 2015

(DOI : 10.1371/journal.pmed.1002087)

Consumption of sugar sweetened beverages, artificially sweetened beverages, and fruit juice and incidence of type 2 diabetes: systematic review, meta-analysis, and estimation of population attributable fraction.

Imamura F, O'Connor L, Ye Z, Mursu J, Hayashino Y, Bhupathiraju SN, and Forouhi NG

BMJ (Clinical research ed.). Jul 2015

(DOI : 10.1136/bmj.h3576)

Positive association between artificially sweetened beverage consumption and incidence of diabetes. Reply to Sylvetsky Meni AC, Swithers SE, Rother KI [letter].

Imamura F, O'Connor L, and Forouhi NG

Diabetologia. Jun 2015

(DOI : 10.1007/s00125-015-3706-5)

Imamura F, O'Connor L, Ye Zheng, Mursu J, Hayashino Y, Bhupathiraju SN, and Forouhi NG

British Journal of Sports Medicine. Jun 2015

(DOI : 10.1136/bjsports-2016-h3576rep)

Physical Activity, Physical Fitness, and Leukocyte Telomere Length: The Cardiovascular Health Study.

Soares-Miranda L, Imamura F, Siscovick D, Jenny NS, Fitzpatrick AL, and Mozaffarian D

Medicine and Science in Sports and Exercise. Jun 2015

(DOI : 10.1249/MSS.0000000000000720)

Dietary quality among men and women in 187 countries in 1990 and 2010: a systematic assessment.

Imamura F, Micha R, Khatibzadeh S, Fahimi S, Shi P, Powles J, Mozaffarian D, and Global Burden of Diseases Nutrition and Chronic Diseases Expert Group (NutriCoDE)

The Lancet. Global health. Feb 2015

(DOI : 10.1016/S2214-109X(14)70381-X)

Consumption of ultra-processed foods and obesity in Brazilian adolescents and adults.

Louzada ML, Baraldi LG, Steele EM, Martins AP, Canella DS, Moubarac JC, Levy RB, Cannon G, Afshin A, Imamura F, Mozaffarian D, and Monteiro CA

Preventive medicine. Feb 2015

(DOI : 10.1016/j.ypmed.2015.07.018)

Association between 25-hydroxyvitamin D and type 2 diabetes--authors' reply.

Forouhi NG, Sharp SJ, Ye Zheng, Imamura F, and Burgess S

The lancet. Diabetes & endocrinology. Jan 2015

(DOI : 10.1016/S2213-8587(14)70247-5)

Contribution of Major Lifestyle Risk Factors for Incident Heart Failure in Older Adults: The Cardiovascular Health Study.

Del Gobbo LC, Kalantarian S, Imamura F, Lemaitre R, Siscovick DS, Psaty BM, and Mozaffarian D

JACC. Heart failure. Dec 2014

(DOI : 10.1016/j.jchf.2015.02.009)

Rice consumption and risk of cardiovascular disease: results from a pooled analysis of 3 U.S. cohorts.

Muraki I, Wu H, Imamura F, Laden F, Rimm EB, Hu FB, Willett WC, and Sun Q

The American Journal of Clinical Nutrition. Dec 2014

(DOI : 10.3945/ajcn.114.087551)

Prospective associations and population impact of sweet beverage intake and type 2 diabetes, and effects of substitutions with alternative beverages.

O'Connor L, Imamura F, Lentjes MA, Khaw KT, Wareham NJ, and Forouhi NG

Diabetologia. Nov 2014

(DOI : 10.1007/s00125-015-3572-1)

Association between circulating 25-hydroxyvitamin D and incident type 2 diabetes: a mendelian randomisation study.

Ye Z, Sharp SJ, Burgess S, Scott RA, Imamura F, InterAct Consortium, Langenberg C, Wareham NJ, and Forouhi NG

The lancet. Diabetes & endocrinology. Oct 2014

(DOI : 10.1016/S2213-8587(14)70184-6)

Circulating and dietary trans fatty acids and incident type 2 diabetes in older adults: the Cardiovascular Health Study.

Wang Q, Imamura F, Ma W, Wang M, Lemaitre RN, King IB, Song X, Biggs ML, Delaney JA, Mukamal KJ, Djoussé L, Siscovick DS, and Mozaffarian D

Diabetes care. Sep 2014

(DOI : 10.2337/dc14-2101)

Differences in the prospective association between individual plasma phospholipid saturated fatty acids and incident type 2 diabetes: the EPIC-InterAct case-cohort study.

Forouhi NG, Koulman A, Sharp SJ, Imamura F, Kröger J, Schulze MB, Crowe FL, Huerta JM, Guevara M, Beulens JW, van Woudenbergh GJ, Wang L, Summerhill K, Griffin JL, Feskens EJ, Amiano P, Boeing H, Clavel-Chapelon F, Dartois L, Fagherazzi G, Franks PW, Gonzalez C, Jakobsen MU, Kaaks R, Key TJ, Khaw KT, Kühn T, Mattiello A, Nilsson PM, Overvad K, Pala V, Palli D, Quirós JR, Rolandsson O, Roswall N, Sacerdote C, Sánchez MJ, Slimani N, Spijkerman AM, Tjonneland A, Tormo MJ, Tumino R, van der A DL, van der Schouw YT, Langenberg C, Riboli E, and Wareham NJ

The lancet. Diabetes & endocrinology. Aug 2014

(DOI : 10.1016/S2213-8587(14)70146-9)

Assessing global dietary habits: a comparison of national estimates from the FAO and the Global Dietary Database.

Del Gobbo LC, Khatibzadeh S, Imamura F, Micha R, Shi P, Smith M, Myers SS, and Mozaffarian D

The American Journal of Clinical Nutrition. Mar 2014

(DOI : 10.3945/ajcn.114.087403)

Fruit consumption and risk of type 2 diabetes: results from three prospective longitudinal cohort studies.

Muraki I, Imamura F, Manson JE, Hu FB, Willett WC, van Dam RM, and Sun Q

BMJ (Clinical research ed.). Aug 2013

(DOI : 10.1136/bmj.f5001)

Study at Cambridge

About the University

Research at Cambridge