MRC Epidemiology Unit
Accumulation of saturated intramyocellular lipid is associated with insulin resistance.
Savage DB, Watson L, Carr K, Adams C, Brage S, Chatterjee KK, Hodson L, Boesch C, Kemp GJ, and Sleigh A
Journal of lipid research. Dec 2018
(DOI : 10.1194/jlr.M091942)
Phillips AC, Sleigh A, McAllister CJ, Brage S, Carpenter TA, Kemp GJ, and Holland AJ
PLoS ONE. Jul 2013
(DOI : 10.1371/journal.pone.0084031)
Mitochondrial oxidative phosphorylation is impaired in patients with congenital lipodystrophy.
Sleigh A, Stears A, Thackray K, Watson L, Gambineri A, Nag S, Campi VI, Schoenmakers N, Brage S, Carpenter TA, Murgatroyd PR, O'Rahilly S, Kemp GJ, and Savage DB
The Journal of clinical endocrinology and metabolism. Jan 2012
(DOI : 10.1210/jc.2011-2587)
Mitochondrial dysfunction in patients with primary congenital insulin resistance.
Sleigh A, Raymond-Barker P, Thackray K, Porter D, Hatunic M, Vottero A, Burren C, Mitchell C, McIntyre M, Brage S, Carpenter TA, Murgatroyd PR, Brindle KM, Kemp GJ, O'Rahilly S, Semple RK, and Savage DB
The Journal of clinical investigation. Jan 2011
(DOI : 10.1172/JCI46405)
